Author: Jacqueline N. PhD Crawley
Transgenic and knockout mutations provide an important means for understanding gene function, as well as for developing therapies for genetic diseases. This engaging and informative book discusses the many advances in the field of transgenic technology that have enabled researchers to bring about various changes in the
mouse genome. Equal emphasis is given to both the principles of transgenic and knockout methods and
their applications. A clear and concise format provides researchers with a comprehensive review of the behavioral paradigms appropriate for analyzing
mouse phenotypes. What's Wrong with My Mouse? explains the differences between transgenic knockout mice and their wild-type
It is a much prized addition... and fulfills a heretofore unmet need for a comprehensive sourcebook of mutant mouse literature and procedures. In addition to its reference utility, Dr. Crawley's text
"I would recommend that every behavioral scientist has at least two copies, one for their own use and one that will be on permanent loan to their students, post-doctoral students and colleagues in