Fundamentals of Clinical Trials
Authors: Lawrence M. Friedman, Curt D. Furberg, David L. DeMets Manufacturer: Springer Keywords: Nursing ISBN: 0387985867
Book description The randomized control clinical trial has become the gold standard scientific method for the evaluation of pharmaceuticals, biologics, devices, procedures and diagnostic tests. This trial design has been successfully used in both therapeutic and disease prevention trials. It is superior to alternative designs by eliminating several sources of bias which exist in those designs. This role has evolved over the past three decades in a number of disease areas including cardiology, opthalmology, cancer and AIDS. While the specifics of using the randomized control design for a specific intervention and disease may differ, the basic fundamentals still apply in developing the study protocol and…
Book review: Good intro textbook I used this book for a class that I took last semester on clinical trial. The authors do a good job of giving a good overview of the topics of interest, in particular: sample size calculation, use of… The fact that this book was designed for researchers, who are involved in experimental (clinical) trials, makes the basic knowledge of statistics essential.Using an interactive multidisciplinary… |
