Authors: Gregory N. Stephanopoulos, Aristos A. Aristidou, Jens Nielsen
Metabolic engineering is a new field with applications in the production of chemicals, fuels, materials, pharmaceuticals, and medicine at the genetic level. The field's novelty is in the synthesis of molecular biology techniques and the tools of
mathematical analysis, which allow rational selection of targets for genetic modification through measurements and control of metabolic fluxes. The objective is to identify specific genetics or environmental manipulations that result in improvements in yield and productivities of biotechnological processes.Key features of the book are
pathway integration and the focus on metabolic flux as a fundamental determinant of cell physiology. The book keeps