Botulinum toxin A is a remarkably versatile treatment with a steadily expanding list of indications, which include strabismus, hemifacial spasm, focal dystonias such as spasmodic torticollis, dysphonia and writer's cramp, as well as adult and childhood spasticity. Recent innovations include its use in some types of pain, in autonomic and
gastrointestinal disorders, and in cosmetic medicine, such as hyperhidrosis, hypersalivation, rectal fissure, achalasia and facial wrinkles. Botulinum toxin is arguably the safest and most effective treatment in
movement disorders since the introduction of levodopa, and is an increasingly important option in many other fields.The long-awaited second edition