This book describes tissue (cell and organ) culture techniques which can be used at a critical predevelopment stage. To screen for
drug-induced toxicity or to analyse the molecular mechanism(s) of toxicity at a later stage in parallel with investigative
in-vivo studies. This type of research has important ethical, financial and scientific implications. In particular, less animals and compound are required for in- vitro research and more detailed information at the cellular and subcellular levels can be obtained. This book brings together the present, disparate knowledge of culture techniques, and thus provides an important
reference work for immediate use by practising industrial and