Authors: M. Isidori, M. Lavorgna, A. Nardelli, L. Pascarella, A. Parrella
Manufacturer: Copyright (c) 2006 Elsevier B.V.
The ecotoxicity of the following six antibiotics on aquatic organisms was investigated: Erythromycin, Oxytetracyclin, Sulfamethoxazole, Ofloxacin,
Lincomycin and Clarithromycin. Bioassays were performed on bacteria, algae, rotifers, microcrustaceans and fish to assess acute and chronic toxicity, while SOS Chromotest and Ames test were used to detect the genotoxic potential of the investigated drugs. For risk assessment, the
environmental impact was calculated by MEC/PNEC ratio using the available data from the literature regarding their occurrence in the
aquatic environment and the toxicity data obtained from the bioassays performed. The ecotoxicological results showed that acute toxicity