This landmark volume discusses the characteristics and impact of the
remodeling process on airway function and clinical disease expression within the airway in asthma, covering pharmacological therapies and possible future targets relevant to regulating the remodeling process. Emphasizes the importance of treating underlying airway inflammation and the relevance of structural alterations to the airway wall, including glandular increases, enhanced collagen deposition within the submucosa, increased vasculature, smooth
hypertrophy, and hyperplasias! Tracing the development and maintenance of
bronchial hyperresponsiveness, decline in lung function, and loss of reversibility evident in chronic…
