Penicillins and cephalosporins have a long history in combating bacterial infections. Despite new infectious diseases and occurring resistance, b-lactam antibiotics will for many years to come continue to play a prominent role in our therapeutic arsenal. This book covers the industrial development of the chemical and biochemical processes used to manufacture these products, as well as looking ahead to possible future processes. The interplay between synthetic organic chemistry with the understanding and application of enzymes, modeling of
fermentation processes and integration through (bio-) chemical process engineering is illustrated. In-depth
scientific approaches to
biocatalysis and…
