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Read book description Studies of the complexation reactions of polyether ionophore antibiotics nigericin and salinomycin with
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Studies of the complexation reactions of polyether ionophore antibiotics nigericin and salinomycin with lead(II), zinc, calcium, magnesium, sodium and potassium cations
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Studies of the complexation reactions of polyether ionophore antibiotics nigericin and salinomycin with lead(II), zinc, calcium, magnesium, sodium and potassium cations


Author: Bo Tan
Manufacturer: ProQuest / UMI
Keywords: Calcium Magnesium and Zinc
ISBN: 0496955101

Book description
Salinomycin and nigericin are members of polyether carboxylic acid ionophores. Recent studies using phospholipid vesicles show that these compounds transport Pb2+ with high selectivity relative to other divalent cations. The purpose of this work is to help explain the high selectivity of these ionophores for lead over other metal ions. CD studies in 80% methanol-water indicate that Pb2+ forms 1: 1 complexes almost quantitatively with monensin, nigericin, narasin, maduramicin, and salinomycin. UV-Vis titrations in 80% methanol-water showed the same result for nigericin and salinomycin. The lead complexes of nigericin and salinomycin were prepared and were subjected to elemental and MS…


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