This volume describes recent research in the field of
metalloproteinases, in particular their participation in autoimmune diseases such as rheumatoid arthritis. The work updates current progress in
matrix metalloproteinase research, reviewing the latest developments in metalloproteinase inhibitor design and the current status of clinical candidates. It elucidates the structural relationships between different members of the MMP family and provides insight into the contributions of different
metalloproteinases to normal and pathological processes. Special emphasis is given to the potential of adamalysins as therapeutic targets. This volume is intended not only for those active in research