Since the mid-1950's,
primary immunodeficiency disorders have been studied intensively as "experiments of nature" to better understand how the immune system works. The recent
progress in immunology, genetics, and molecular biology has introduced a new dimension in our understanding of these diseases: scientists and clinicians can now precisely identify many inherited defects on the molecular level and perform mutation analysis, confirm the diagnosis, screen for carriers, and begin to work on gene therapy. NLThis book reviews our present understanding of immunology, genetics, and molecular biology and focuses on each of the genetically determined primary
immunodeficiency disorders. It…
