An important new collection of clinical and preclinical
reports on genetic therapy, this book describes illustrative examples of diseases in which gene-based interventions are presently plausible, and presents case studies of current research using both synthetic oligonucleotides and biological vectors. Combining the insights of over 50 contributors, Clinical Trials of
Genetic Therapy with Antisense DNA and DNA Vectors · furnishes a historical overview of genetic therapy · highlights official Food and Drug Administration positions on the preparation of oligonucleotides and vectors · offers practical models of agent preparation, animal testing, pharmacokinetics, toxicology, and clinical…
