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Generic pheniramine information

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Generic Drug: pheniramine
Brand Name: Pheniramine Maleate

Active Ingredient: pheniramine maleate
Dose Form Description: powder
Route Description: compounding

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Induction of endoplasmic reticular stress by bortezomib: A novel therapeutic strategy for pancreatic cancer

Induction of endoplasmic reticular stress by bortezomib: A novel therapeutic strategy for pancreatic cancer

Author: Steffan Todd Nawrocki
Manufacturer: ProQuest / UMI
Keywords: bortezomib
ISBN: 0542042169

Book description
Bortezomib (VELCADE™, formerly known as PS-341) is a selective and potent inhibitor of the proteasome that was recently FDA-approved for the treatment of multiple myeloma. Despite its success in multiple myeloma and progression into clinical trials for other malignancies, bortezomib's exact mechanism of action remains undefined. The major objective of this study was to evaluate the anticancer activity of this drug using in vitro and in vivo pancreatic cancer models and determine whether bortezomib-induced apoptosis occurs via induction of endoplasmic reticular (ER) stress. The investigation revealed that bortezomib inhibited tumor cell proliferation via abrogation of cdk activity and…
Biochemistry text books: Morbid Obesity: Peri-Operative Management, Cancer and Vitamin C: A Discussion of the Nature, Causes, Prevention, and Treatment of Cancer With Special Reference to the Value of Vitamin C, Mosby's Rapid Review Series: Maternal-Child Nursing (Book with CD-ROM for Windows Macintosh), Phase I Cancer Clinical Trials: A Practical Guide, Basic Concepts in Immunology: Single User Edition (Topics in Biosciences)

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