Authors: Milan Potmesil, H. M. Pinedo
This exciting new book presents the first comprehensive overview of clinical trials of
camptothecins, a new class of anticancer agents. Camptothecins are synthetic and semisynthetic derivatives of a plant alkaloid that inhibit a cellular enzyme and trigger a cascade of events leading to
programmed cell death. Special attention is given to the adverse effects of camptothecin treatment, as well as to prevention and control. The book boasts contributions by some of the most respected authorities in camptothecin research, who haveoConducted much of the pre-clinical work which helped to
renew interest in camptothecinsoDiscovered and identified the natural product camptothecin and synthesized most…
