Authors: H. Vainio, P. Magee, D. McGregor, A. J. McMichael
This comprehensive, authoritative volume includes a consensus document drawn up by a working group of international experts in various fields of carcinogenesis. It describes the multistage and multifactorial nature of carcinogenesis, the different mechanisms of action of carcinogens, epidemiological and laboratory means for their identification, and proposed principles and procedures for their possible use in the prediction and evaluation of
carcinogenic risks to humans. Other chapters cover critical molecular targets in
chemical carcinogenesis; mechanisms of carcinogenicity;animal carcinogenicity tests and their interpretations; biological markers in exposed humans; and data analysis and