This volume contains the
papers presented at a meeting held in December 1985 to review the conduct and use of long- and short- term assays for the detection of chemical carcinogens. The meeting was attended by about 60 experts in the fields of carcinogenesis,
mutagenesis, and cell biology.The series of reports on long-term
carcinogenicity assays pay particular attention to three topics: the role of pharmacokinetic data, early preneoplastic lesions in carcinogenesis, and the possibility for discerning the relative contribution of carcinogens to various stages of carcinogenesis. Thereports on short-term assays summarize, among other points, the principle and scientific basis of each assay and…
