Generic proparacaine ophthalmic information

Generic Drug: proparacaine ophthalmic

Brand Names: AK-Taine, Alcaine, Ocu-Caine, Ophthaine, Ophthetic, Parcaine, Proparacaine Hydrochloride

Active Ingredient: proparacaine hydrochloride
Dose Form Descriptions: powder; solution
Route Descriptions: compounding, ophthalmic
Proparacaine ophthalmic Strength Description: 0.5%

What is proparacaine ophthalmic?
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The molecular mechanisms underlying the in vitro immunostimulatory and toxic effects of the antifungal drug, amphotericin B: Role of Toll-like receptor 2 and CD14

Author: Keya Sau

Manufacturer: ProQuest / UMI

Keywords: Amphotericin B

Rubric: Pharmaceutical drug books

ISBN: 0496904205

Book description

The primary clinical limitation of the broad-spectrum antifungal compound, amphotericin B (AmB), is its significant toxicity. Hence AmB is no longer the first line of defense against many deep-seated fungal infections, though it is inexpensive and efficacious. We hypothesized that AmB utilizes receptors highly represented in the innate immune cell repertoire, specifically Toll-like receptors (TLR) and the cluster of differentiation-14 antigen (CD14) co-receptor, to elicit toxic effects. We based this hypothesis principally on 3 underlying facts: (1) AmB's toxic effects are inflammatory in nature, (2) AmB is a product of the Gram-positive bacterium, Streptomyces nodosus, and (3) TLR are…

Pharmaceutical drug books: The Web of Life, Acsm Fitness Book, Evidence Based Dermatology

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