Authors: William B. Pratt, Raymond W. Ruddon, William D. Ensminger, Jonathan Maybaum
This text offers an up-to-date review of the field of cancer chemotherapy, including some of the new approaches to biological treatments of cancer and potential
targets for new drug design. A detailed description of the pharmacology, mechanisms of action, toxicity, resistance mechanisms, andclinical usefulness of each class of drugs is given. The authors emphasize concepts involved in determining the mechanism of action and development of resistance, the
determinants of drug responsiveness to chemotherapeutic agents, and a rationale for
their clinical use in various types of cancer. The text is organized in a way that makes it easy for the reader to conceptualize how drugs work and…
