This two-volume set provides a full account of the entire sequence of drug development,
from conceptualizing the drug, creating a library of candidates, and conducting clinical trials, to optimizing the synthetic route, marketing the drug, and developing delivery methods. Comprehensive in scope, the set bridges the gap between medicinal and process chemistry. Discussion includes the discovery of agents for the treatment and management of bacterial infections,
Parkinson's disease, psoriasis,
ulcers and stomach pain, atopic dermatitis, asthma, and cancer. Case studies examine the discovery of erythromycin analogs (antibiotics), Tagamet, and Ultiva (remifentanil). Full chapters are devoted to…
