Authors: T.J. Cleophas, A.H. Zwinderman, T.F. Cleophas
The previous two editions of this book, rather than being comprehensive, concentrated on the most relevant aspects of statistical analysis. Although well-received by students, clinicians, and researchers, these editions did not answer all their questions. This updated and extended edition serves as a more complete guide and reference text to students, physicians, and investigators, and, at the same time, preserves the
common sense approach to statistical problem-solving of the previous editions. In 1948 the first randomized controlled trial was published by the English
Medical Research Council in the British Medical Journal. Until then, observations had been uncontrolled. Initially, trials…
