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Read book description Tackling ErbB2: ErbB2-targeting peptide therapy and combination therapy with trastuzumab plus PI3K
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Generic Sulfacet Sodium information



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generic sulfacet sodium information

Brand Name: Sulfacet Sodium
Generic Drug: sulfacetamide sodium ophthalmic

Active Ingredient: sulfacetamide sodium
Dose Form Description: solution
Route Description: ophthalmic
Sulfacet Sodium Strength Description: 10%

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Apotex Corporation

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Tackling ErbB2: ErbB2-targeting peptide therapy and combination therapy with trastuzumab plus PI3K inhibitors
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Tackling ErbB2: ErbB2-targeting peptide therapy and combination therapy with trastuzumab plus PI3K inhibitors


Author: Keng-Hsueh Lan
Manufacturer: ProQuest / UMI
Keywords: trastuzumab
ISBN: 0542042134

Book description
ErbB2 is an excellent target for cancer therapies because its overexpression was found in about 30% of breast cancers and correlated with poor prognosis of the patients. Unfortunately, current therapies for ErbB2-positive breast cancers remain unsatisfying due to side effects and resistance, and new therapies for ErbB2 overexpressing breast cancers are needed. Peptide/protein therapy using cell-penetrating peptides (CPPs) as carriers is promising because the internalization is highly efficient and the cargos can be bioactive. The major obstacle in using CPPs for therapy is their lack of specificity. We sought to develop a peptide carrier specifically introducing therapeutics to…


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