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Effect of oral acamprosate on abstinence in patients with alcohol dependence in a double-blind, placebo-controlled trial: The role of patient motivation

Authors: B.J. Mason, A.M. Goodman, S. Chabac, P. Lehert

Keywords: acamprosate

Rubric: Drug delivery books

ISBN: B000HDZHVC

Book description

This is the first US study to evaluate the clinical efficacy of acamprosate (Campral), a newly FDA-approved medication for maintaining abstinence in patients with alcohol dependence following alcohol withdrawal. We compared effects of the standard 2g dose (n=258) and an exploratory 3g dose of acamprosate (n=83) versus placebo (n=260), and evaluated drug safety in a double-blind, placebo-controlled 6-month trial conducted in 21 outpatient clinics across the US. Participants were 601 volunteers with current alcohol dependence recruited primarily by advertisement. All patients concomitantly received eight sessions of brief manual-guided counseling (www.alcoholfree.info). The main outcome…

Drug delivery books: High-Yield Comprehensive USMLE Step 1 Review (High-Yield Series), No More Allergies: Identifying and Eliminating Allergies and Sensitivity Reactions to Everything in Your Environment (The Gary Null Natural Health Library), Microbial Contamination Control in the Pharmaceutical Industry (Drugs and the Pharmaceutical Sciences: a Series of Textbooks and Monographs)

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