Author: Erwin v. Angerer
This book is about the estrogen receptor as a biochemical target for the design of new agents useful for the therapy and diagnosis of estrogen-related diseases such as carcinomas of the breast, the endometrium, the ovaries and the prostate, osteoporosis, and benign prostate hyperplasia. Some of these drugs have also become valuable tools for investigating the molecular mode of action of
estrogens and
their antagonists. The book describes the rational design of potent anti-estrogens, estrogen-linked cytostatics and radioisotope-labeled steroids and gives guidelines for
further developments.
