This is the first comprehensive work to showcase the useful diversity of
cellular effects elicited by nitric oxide. A collection of expert contributors provides cutting-edge information on a variety of topics with tremendous implications in biology and medicine. These include nitric oxide-driven cell signaling; nitric oxide's role in hypoxia, gene expression, gene regulation in
pulmonary pathophysiology,
cell metabolism modulation, and tumor biology; and the intriguing concept of mitochondrial nitric oxide synthase as a regulator of mitochondrial bioenergetics and free radical production.