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Read book description Pharmacokinetics of morphine in fish: Winter flounder (Pseudopleuronectes americanus) and
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Generic Uni-Multihist D Ped information



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generic uni multihist d ped information

Brand Name: Uni-Multihist D Ped
Generic Drug: pheniramine/ PPA/ phenyltoloxamine/ pyrilamine

Active Ingredients: pheniramine maleate; phenylpropanolamine hydrochloride; phenyltoloxamine citrate; pyrilamine maleate
Dose Form Description: capsule, extended release
Route Description: oral
Uni-Multihist D Ped Strength Description: 8 mg-25 mg-8 mg-8 mg

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United Research Laboratories/Mutual Pharmaceutical Company

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Pharmacokinetics of morphine in fish: Winter flounder (Pseudopleuronectes americanus) and seawater-acclimated rainbow trout (Oncorhynchus mykiss)
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Pharmacokinetics of morphine in fish: Winter flounder (Pseudopleuronectes americanus) and seawater-acclimated rainbow trout (Oncorhynchus mykiss)


Authors: N.C. Newby, P.C. Mendonca, K. Gamperl, E.D. Stevens
Keywords: P-A-C Analgesic
ISBN: B000HBJY6S

Book description
We made a single intraperitoneal (IP) injection of morphine sulfate (40mg/kg) into winter flounder and seawater acclimated rainbow trout at 10^oC and then followed its disposition by measuring the change in plasma morphine concentration for 100h using a morphine specific ELISA. Disposition also was followed for 6h after a single IV injection of 7.5mg morphine sulfate in winter flounder. Plasma morphine reached a maximum within an hour post-injection IP and then decreased in a bi-exponential fashion with a rapid distribution phase followed by a slower elimination phase. The disposition was slower in flounder than in trout even though the fish were held at the same temperature. For example…


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