Author: Wendell W. Weber
This comprehensive account of hereditary acetylation in humans and animals is based on the premise that varied individual responses to drugs, chemicals, and carcinogens are profoundly influenced by genetic factors. Acetylation, the mechanism by which the body disposes of many chemicalsencountered in everyday life, presents a unique example of how a multiplicity of
genetically determined differences in drug response can arise from a single metabolic theme, and of how the understanding of a pharmacogenetic trait can be used to prevent human illness of environmental origin. Thismonograph assesses the role of drug acetylation as a genetic factor capable of altering
susceptibility to therapeutic…
