The experience gained with tamoxifen has been the basis for the new concept of
selective estrogen receptor modulators (SERMs). The action of these substances has been investigated in both basic and clinical studies, but there is not an integrated view of all the facets of this recent area in modern medicine. This book offers an up-to-date compilation of the most relevant information on the topic carried out by experienced basic and clinical investigators. The first section revises the basic determinants required to understand the
functional versatility of SERMs. This part includes chapters that review the main SERM families and their principal components, the mechanisms of action of steroid…
